Additional file 1 of Association of alcohol consumption with morbidity and mortality in patients with cardiovascular disease: original data and meta-analysis of 48,423 men and women

Additional file 1: Supplementary Materials. Supplementary methods for de novo cohort analyses (Appendix S1 and Table S1). Quality assessment checklist (Appendix S2). Literature search strategy (Table S2). Alcohol consumption, effect estimates, and confounder adjustment reported by studies selected for meta-analyses (Table S3-S5). Associations of alcohol intake with HDL-cholesterol and gamma-glutamyl transferase in UK Biobank and HSE/SHeSs (Table S6). Schoenfeld residuals (Figure S1). Results of subgroup and sensitivity analyses for dose-response relationship between alcohol consumption and risk of all-cause mortality, cardiovascular mortality, and cardiovascular events (Figure S2, S7-S12). Patients inclusion flowchart for HSE/SHeSs and UK Biobank (Figure S3). Association of drinking categories with all-cause mortality, cardiovascular mortality, and cardiovascular events by cohort, sex, and primary events (Figure S4-S5). Study flow diagram (Figure S6). Funnel plots (Figure S13).