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Additional file 1 of Alcohol related hepatitis in intensive care units: clinical and biological spectrum and mortality risk factors: a multicenter retrospective study

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posted on 2025-04-15, 03:28 authored by Maxime Gasperment, Léa Duhaut, Nicolas Terzi, Côme Gerard, Luc Haudebourg, Alexandre Demoule, Mialy Randrianarisoa, Vincent Castelain, Sacha Sarfati, Fabienne Tamion, Charlene Le Moal, Christophe Guitton, Gabriel Preda, Arnaud Galbois, Thibault Vieille, Gaël Piton, Marika Rudler, Guillaume Dumas, Hafid Ait-Oufella
Supplementary Material 1: Additional file 1: Study flow chart. ARH, Alcohol Related Hepatitis. Additional file 2: Number of alcohol related hepatitis patients included in each center. Additional file 3: Predictive factors of ICU mortality (univariate analysis). SOFA, Sequential Organ Failure Assessment; SAPS II, Simplified Acute Physiology Score; MELD, Model for End-stage Liver Disease; INR, International Normalized Ratio. Additional file 4: Comparison between patients treated and not treated with corticosteroids (only patients for which corticosteroids were initiated no more than three days prior to ICU admission were included). SOFA, Sequential Organ Failure Assessment; SAPS II, Simplified Acute Physiology Score; INR, International Normalized Ratio; ARH, Alcohol Related Hepatitis. Additional file 5: Propensity score distribution, before and after weighting. Additional file 6: Balance checks after weighting on propensity score for corticosteroids use: absolute standardized mean difference before and after weighing (panel A) and cumulative frequencies of main continuous predictors (panel B). PT, Prothrombin Time; SOFA, Sequential Organ Failure Assessment; MELD, Model for End-stage Liver Disease; ARF, Acute Respiratory Failure; AKI, Acute Kidney Failure. Additional file 7: Cumulative incidence of death according to corticosteroids therapy on the weighted sample. Additional file 8: Comparison between patients in which a liver biopsy was or was not performed (only patients for which corticosteroids were initiated no more than three days prior to ICU admission were included). ARH, Alcohol Related Hepatitis; INR, International Normalized Ratio; SOFA, Sequential Organ Failure Assessment; SAPS II, Simplified Acute Physiology Score; MELD, Model for End-stage Liver Disease.

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