13059_2023_3060_MOESM15_ESM.docx (683.98 kB)
Additional file 15 of Dominance is common in mammals and is associated with trans-acting gene expression and alternative splicing
journal contribution
posted on 2023-11-21, 05:36 authored by Leilei Cui, Bin Yang, Shijun Xiao, Jun Gao, Amelie Baud, Delyth Graham, Martin McBride, Anna Dominiczak, Sebastian Schafer, Regina Lopez Aumatell, Carme Mont, Albert Fernandez Teruel, Norbert Hübner, Jonathan Flint, Richard Mott, Lusheng HuangAdditional file 15. Review history.
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Biotechnology and Biological Sciences Research Council
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wide association studiesthree mammalian stocksrat heterogeneous stockgene expression exhibitsalternatively spliced isoformsacting gene expressionimmunological traits exhibitheritable variance acrossgene expression traitsquantitative trait locimice heterogeneous stockheterogeneous stock ratsf2 intercross pigsconclusions although heritabilityacting expression qtlshighest dominance variancelocus interaction —dominance physiological qtlsacting dominance eqtlsphysiological traitsdominance variancedominance —acting eqtlsquantitative geneticsmice respectivelydominance effectsdominance accountsadditive qtlsuncover causalitytherefore advantageoussystematically investigatepossible mechanismphysically linkedphenomena playone quartermajor rolelikely ariseless likelylarge fractionimprove poweridentify 154genes causaleven thoughdistinct mechanisms
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