13059_2021_2262_MOESM13_ESM.pdf (955.57 kB)
Additional file 13 of Integrative analyses of TEDDY Omics data reveal lipid metabolism abnormalities, increased intracellular ROS and heightened inflammation prior to autoimmunity for type 1 diabetes
journal contribution
posted on 2021-01-23, 00:47 authored by Leandro Balzano-Nogueira, Ricardo Ramirez, Tatyana Zamkovaya, Jordan Dailey, Alexandria N. Ardissone, Srikar Chamala, Joan Serrano-Quílez, Teresa Rubio, Michael J. Haller, Patrick Concannon, Mark A. Atkinson, Desmond A. Schatz, Eric W. Triplett, Ana ConesaAdditional file 13. Supplementary figures.
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Leona M. and Harry B. Helmsley Charitable Trust Juvenile Diabetes Research Foundation United States of America
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islet autoantibodieslipid metabolismintracellular ROS accumulationlipid metabolism abnormalities1 yearmulti-omics approachdisease biomarkersinflammationantigen-presenting cellsislet autoimmunitystudy type 1 diabetesmultifactorial diseasesintracellular ROSIA-developing children monthstype 1 diabetes Abstract Backgroundmulti-omics signatureTEDDY Omics dataEnvironmental DeterminantsIntegrative analysesT 1DTEDDY cohort showcasesextracellular matrixmulti-omics databeta cell destructionabnormalitybirth cohortislet autoimmunity etiology
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