12967_2016_1030_MOESM7_ESM.tif (4.49 MB)
MOESM7 of Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study
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posted on 2016-09-29, 05:00 authored by Sarah White, Mary McDermott, Robert Sufit, Kate Kosmac, Alex Bugg, Marta Gonzalez-Freire, Luigi Ferrucci, Lu Tian, Lihui Zhao, Ying Gao, Melina Kibbe, Michael Criqui, Christiaan Leeuwenburgh, Charlotte PetersonAdditional file 7: Figure S7. Representative confocal images of PAD gastrocnemius muscle sections. A) LC3 (red) is diffuse throughout cavity where mitochondrial cytochrome c oxidase protein (complex IV; COX-1; green) is absent. B) LC3 has formed a plaque in the center of the COX-1 protein cavity. Scale bar = 10 ÂľM.
