12864_2019_6265_MOESM5_ESM.tif (355.17 kB)

MOESM5 of Infection and RNA-seq analysis of a zebrafish tlr2 mutant shows a broad function of this toll-like receptor in transcriptional and metabolic control and defense to Mycobacterium marinum infection

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posted on 21.11.2019 by Wanbin Hu, Shuxin Yang, Yasuhito Shimada, Magnus Münch, Rubén Marín-Juez, Annemarie Meijer, Herman Spaink
Additional file 5: Figure S5. Volcano plots showing the significance cutoff applied to tlr2+/− infected with strain Mma20 versus control with PBS (a) and tlr2−/− infected with strain Mma20 versus control with PBS (b). In these volcano plots, the transcripts were considered significant (red) or non-significant (blue) by the conditions of |fold change| ≥ 1,45 and adjusted P value threshold ≤ 0,05. Fold changes for each transcript was plotted on the X-axis against -log10 transformed p-values on the Y-axis.

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