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MOESM4 of Walking performance is positively correlated to calf muscle fiber size in peripheral artery disease subjects, but fibers show aberrant mitophagy: an observational study

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posted on 2016-09-29, 05:00 authored by Sarah White, Mary McDermott, Robert Sufit, Kate Kosmac, Alex Bugg, Marta Gonzalez-Freire, Luigi Ferrucci, Lu Tian, Lihui Zhao, Ying Gao, Melina Kibbe, Michael Criqui, Christiaan Leeuwenburgh, Charlotte Peterson
Additional file 4: Figure S4. Lectin staining to quantify capillary density. Representative images of lectin binding to endothelial cells in non-PAD (A) and PAD (B) gastrocnemius muscle sections. C) Quantification of lectin staining, expressed as lectin+ capillaries/fiber in PAD (n=18) compared to non-PAD (n=7) participants (ANOVA, P=0.082). Approximately 600 fibers were analyzed per subject. Data represented as Mean Âą SEM. Scale bar = 50 Âľm.


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