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MOESM3 of Pharmacological inhibition of Bmi1 by PTC-209 impaired tumor growth in head neck squamous cell carcinoma
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posted on 2017-11-21, 05:00 authored by Qiong Wang, Zhongwu Li, Yaping Wu, Rong Huang, Yumin Zhu, Wei Zhang, Yanling Wang, Jie ChengAdditional file 3: Figure S2. Global ubiquitinated histone 2A (uH2A), the hallmark of Bmi1-mediated repressive chromatin structures and transcriptional silencing, is significantly downregulated upon PTC-209 treatment (10Â ÎźM, 48Â h). The representative images of western blot are shown.
