Springer Nature
Browse
13045_2020_1029_MOESM8_ESM.tif (287.68 kB)

Additional file 8 of STOML2 potentiates metastasis of hepatocellular carcinoma by promoting PINK1-mediated mitophagy and regulates sensitivity to lenvatinib

Download (287.68 kB)
figure
posted on 2021-01-15, 04:27 authored by Yahui Zheng, Chong Huang, Lu Lu, Kangkang Yu, Jing Zhao, Mingquan Chen, Lu Liu, Qingfeng Sun, Zhifei Lin, Jianming Zheng, Jinhong Chen, Jubo Zhang
Additional file 8: Figure S6. STOML2 is a target of HIF-1α. (A) HRE in the STOML2 promoter identified by the JASPAR database ( http://jaspar.genereg.net/ ). (B) Schematic illustration of STOML2 promoter region with potential HIF-1α binding site. The WT and HRE mutant sequences were indicated.

Funding

National Natural Science Foundation of China (CN) National Natural Science Foundation of China Natural Science Foundation of Shanghai Zhejiang Province Public Welfare Technology Application Research Project National Key Scientific Instrument and Equipment Development Projects of China

History

Usage metrics

    Journal of Hematology & Oncology

    Categories

    Keywords

    Stomatin-like protein 2 (STOML2)Hepatocellular carcinoma (HCC)PTEN-induced putative kinase 1 (PINK1)MitophagyLenvatinib

    Licence

    CC BY + CC0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC