Additional file 8: of Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma
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posted on 2019-06-17, 05:00 authored by Noah Berlow, Rishi Rikhi, Mathew Geltzeiler, Jinu Abraham, Matthew Svalina, Lara Davis, Erin Wise, Maria Mancini, Jonathan Noujaim, Atiya Mansoor, Michael Quist, Kevin Matlock, Martin Goros, Brian Hernandez, Yee Doung, Khin Thway, Tomohide Tsukahara, Jun Nishio, Elaine Huang, Susan Airhart, Carol Bult, Regina Gandour-Edwards, Robert Maki, Robin Jones, Joel Michalek, Milan Milovancev, Souparno Ghosh, Ranadip Pal, Charles KellerFigure S8. Low dose combination validation results for drug combinations GDC-0941 + OSI-906. Results are based on n = 3 technical replicates with n = 4 replicates per treatment condition. (A) Dose response curve for OSI-906 varied dosage + GDC-0941 low fixed dosage. The response for GDC-0941 at varied dosages is included. (B) Dose response curve for GDC-0941 varied dosage + OSI-906 low fixed dosage. The response for OSI-906 at varied dosages is included. (TIF 10578 kb)
