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Additional file 8: Figure S4. of Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts
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posted on 2016-08-03, 05:00 authored by Pierre De Rossi, Virginie Buggia-Prévot, Benjamin Clayton, Jared Vasquez, Carson van Sanford, Robert Andrew, Ruben Lesnick, Alexandra Botté, Carole Deyts, Someya Salem, Eshaan Rao, Richard Rice, Angèle Parent, Satyabrata Kar, Brian Popko, Peter Pytel, Steven Estus, Gopal ThinakaranThe distribution of BIN1 in rat brain. BIN1 staining is in green and nuclei stained with Hoechst are in blue. (A and B) Immunofluorescence staining of coronal sections with antibodies N-19 or 2F11 reveals BIN1 immunoreactivity in the cortex with intense straining of the corpus callosum (CC). (C and D) Higher magnification images of 2F11 staining of oligodendrocytes dispersed in the cortex and arranged as linear arrays in the corpus callosum. (TIFF 5477 kb)