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Additional file 7 of The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer’s disease

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posted on 2023-09-30, 03:22 authored by Amanda L. Wright, Lyndsey M. Konen, Bruce G. Mockett, Gary P. Morris, Anurag Singh, Lisseth Estefania Burbano, Luke Milham, Monica Hoang, Raphael Zinn, Rose Chesworth, Richard P. Tan, Gordon A. Royle, Ian Clark, Steven Petrou, Wickliffe C. Abraham, Bryce Vissel
Additional file 7: Sup. Figure 7. Synaptic transmission and short-term plasticity. (a) Input/output ratios and (b) paired pulse facilitation remain unchanged in all genotypes (n’s: WT = 24 slices (a) and 26 slices (b) from 9 mice, GluA2G/G = 21 slices from 7 mice, J20 = 24 slices from 7 mice, GluA2G/G/J20 = 13 slices from 7 mice; input/output ratio two-way RM ANOVA: genotype effect F(3,81)  =  0.386, p = 0.76; PPF two-way RM ANOVA: genotype effect F(3,81)  =  0.386, p = 0.76). Each value represents the mean ± the SEM.

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National Health and Medical Research Council The Boyarsky Family Trust The Howland-Rose Foundation Douglas and Alison Battersby - Veruse Pty Ltd David and Lynn King John and Debbie Schaffer Lady Fairfax Charitable Trust Stanley and Charmaine Roth Foundation Iain Gray

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    Molecular Neurodegeneration

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