Additional file 6 of The MYC/TXNIP axis mediates NCL-Suppressed CD8+T cell immune response in lung adenocarcinoma

Supplementary Material 6: Figure S6. Impact of TXNIP on Glucose Metabolism Reprogramming in CD8+ T Cells. Notes: (A) Glucose uptake levels in CD8+ T cells of each group; (B) Lactate production levels in CD8+ T cells of each group; (C) Changes in ECAR in CD8+ T cells of each group, along with the minimum and maximum ECAR values; (D) Changes in OCR in CD8+ T cells of each group, along with the minimum and maximum OCR values; (E) ATP levels determined by ATP assay kit in CD8+ T cells of each group; (F) Mitochondrial membrane potential assessed by flow cytometry in CD8+ T cells of each group using JC-1 signal, and calculation of the red/green signal ratio of JC-1 to determine mitochondrial potential; (G) Expression levels of GLUT1, GLUT4, HK2, LDHA, and LDHB in CD8+ T cells of each group detected by RT-qPCR. All cellular experiments were repeated three times, * indicates P <, ** indicates P <, *** indicates P<.