Additional file 6: Figure S5. of MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1

MicroRNA 195 and PLX-4032 effects in UACC-62 melanoma cells. UACC-62 cells were transfected with either miR-control/miR-195 (25 nM). After 24 h, cells were treated with 1 or 10 μM vemurafenib (PLX-4032) for 48 hs and cell death was determined by flow cytometry after propidium iodide staining. Statistical analysis was carried out using Two-Way ANOVA followed by Bonferroni post-test and are reported by mean ± SD. Representative data of three independent experiments are reported. ***P ≤ 0.001. (JPEG 222 kb)