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Additional file 5 of An epistatic interaction between pre-natal smoke exposure and socioeconomic status has a significant impact on bronchodilator drug response in African American youth with asthma

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posted on 2020-07-04, 03:47 authored by J. Magaña, M. G. Contreras, K. L. Keys, O. Risse-Adams, P. C. Goddard, A. M. Zeiger, A. C. Y. Mak, J. R. Elhawary, L. A. Samedy-Bates, E. Lee, N. Thakur, D. Hu, C. Eng, S. Salazar, S. Huntsman, T. Hu, E. G. Burchard, M. J. White
Additional file 5: Supplemental Figure 1. Full range of Bronchodilator Drug Response Distribution by Pre-natal and Socioeconomic Status (PSE x SES) Interaction Group Membership. Grouped Box Plot Graph of Bronchodilator Drug Response by PSE x SES interaction group membership. Vertical lines denote the group minimum and maximum values, dots represent potential outliers. Boxes represent the interquartile range (IQR) of group data; horizontal lines within boxes indicate the group median. Box color indicates dataset (full, male-only, female-only). Blue horizontal line indicates threshold for clinical response to bronchodilator treatment (∆ FEV1 ≥ 12%). ∆ FEV1 is the difference in % of Predicted FEV1 achieved before and after bronchodilator treatment. ▼ means that the group median < study population median; ▲ means that the group median ≥ study population median. PSE denotes pre-natal smoke exposure, while SES indicates socioeconomic status.

Funding

National Heart, Lung, and Blood Institute National Institute of Environmental Health Sciences National Institute on Minority Health and Health Disparities Tobacco-Related Disease Research Program Gordon and Betty Moore Foundation National Institutes of Health National Institute of General Medical Sciences

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