Additional file 5 of A dysfunctional endolysosomal pathway common to two sub-types of demyelinating Charcot–Marie–Tooth disease

ML-SA1 reduces the frequency of vacuolar endocytic compartments from T115N LITAF patient fibroblasts, and FIG4KO fibroblasts. Conventional electron microscopy of T115N fibroblasts (a) and FIG4 KO fibroblasts (b) without and with treatment with ML-SA1 (40μM, 36 h).