12885_2016_2337_MOESM5_ESM.tif (9.12 MB)

Additional file 5: Figure S5. of Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet

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posted on 2016-05-13, 05:00 authored by Danielle Lussier, Eric Woolf, John Johnson, Kenneth Brooks, Joseph Blattman, Adrienne Scheck

Gating strategies for cytokine expression of CD8+ T cells. Tumor-infiltrating lymphocytes (TILs) isolated from gliomas from mice fed KD versus SD were cultured alone or in the presence of GL261-Luc2 tumor cells. Analysis of IFNÎł (A), TNF (B) and IL-2 (C) production in tumor-infiltrating CD8+ T cells was performed. Percentage of positive cells indicated on plots. (TIF 9343Â kb)

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Students Supporting Brain Tumor Research

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Glioblastoma Glioma Ketogenic diet Metabolism Immunosuppression Microenvironment Immune inhibitory checkpoints Immunology CTLA-4 PD-1

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