12974_2017_997_MOESM5_ESM.jpg (118.47 kB)

Additional file 5: Figure S5. of Blocking ATP-sensitive potassium channel alleviates morphine tolerance by inhibiting HSP70-TLR4-NLRP3-mediated neuroinflammation

Download (118.47 kB)
figure
posted on 25.11.2017 by Jie Qu, Xue-You Tao, Peng Teng, Yan Zhang, Ci-Liang Guo, Liang Hu, Yan-Ning Qian, Chun-Yi Jiang, Wen-Tao Liu
Anti-HSP70 neutralizing antibody did not affect acute morphine analgesic effect. Morphine (10 μg/10 μL, i.t.) with or without anti-HSP70-neutralizing antibody (200 μg/kg, i.t.) were injected into mice and analgesia was assessed at the first day. (n = 6) (data were analyzed by two-way ANOVA). (JPEG 118 kb)

Funding

National Natural Science Foundation of China

History

Exports