Additional file 4 of Nucleoporin 153 deficiency in adult neural stem cells defines a pathological protein-network signature and defective neurogenesis in a mouse model of AD
Version 2 2024-12-06, 04:28
Version 1 2024-09-05, 09:39
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posted on 2024-09-05, 09:39 authored by Claudia Colussi, Alessia Bertozzi, Lucia Leone, Marco Rinaudo, Raimondo Sollazzo, Federica Conte, Elena Paccosi, Luca Nardella, Giuseppe Aceto, Domenica Donatella Li Puma, Cristian Ripoli, Maria Gabriella Vita, Camillo Marra, Marcello D’Ascenzo, Claudio GrassiSupplementary Figure 4: (A) Confocal images showing iPSCs from healthy controls and AD patients labelled for the stem cell markers Sox2, TRA-1, Oct4, Nanog and SSEA4. (B) Western blot evaluation of Nanog, Oct4 and Sox2 in control and AD iPSCs and relative quantification. Differences were found in Sox2 levels. (C-D) Confocal analysis and western blot showing the levels of Nup153 in iPSCs from control and AD samples. *P < 0.05, ** P < 0.01
