12929_2018_479_MOESM3_ESM.tif (2.13 MB)

Additional file 3: of Znf179 E3 ligase-mediated TDP-43 polyubiquitination is involved in TDP-43- ubiquitinated inclusions (UBI) (+)-related neurodegenerative pathology

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posted on 08.11.2018, 05:00 by Yi-Chao Lee, Wan-Chen Huang, Jiann-Her Lin, Tzu-Jen Kao, Hui-Ching Lin, Kuen-Haur Lee, Hsin-Chuan Lin, Che-Kun Shen, Wen-Chang Chang, Chi-Chen Huang
Figure S3. (A) Immunoprecipitated mice whole brain lysates with anti-Znf179 antibody from wild-type and Znf179 knockout mice were separated by SDS-PAGE (4–20% polyacrylamide gel). Protein lands corresponding to immuno-positive bands were excised from gels (a, b, c and d bands), and analyzed with mass spectrometer. (B and C) Potential networks and involved subcellular pathways of identified proteins were further analyzed by IPA. (TIF 2176 kb)


Taipei Medical University Hospital