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Additional file 3: of The lncRNA MIR2052HG regulates ERα levels and aromatase inhibitor resistance through LMTK3 by recruiting EGR1

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posted on 03.04.2019, 05:00 by Junmei Cairns, James Ingle, Krishna Kalari, Lois Shepherd, Michiaki Kubo, Matthew Goetz, Richard Weinshilboum, Liewei Wang
Figure S1. LMTK3 mediates MIR2052HG- regulation of ERα. a Overexpression of LMTK3 in MIR2052HG knocked-down MCF7/AC1 and CAMA-1 cells did not change AKT and FOXO3 mRNA levels. b Expression profiles of ER target genes in MCF7/AC1 and CAMA-1 cells. Cells were transfected with ASO and LMTK3 plasmid. RNA was prepared 24 h following transfection. c Effects of MIR2052HG and LMTK3 on the ability of PKC to phosphorylate its substrates. (TIF 1963 kb)