Additional file 3: of Microglia affect α-synuclein cell-to-cell transfer in a mouse model of Parkinson’s disease

Figure S3. Stereological counts of grafted after AAV injection. a There was no significant difference (p > 0.05) in the total number of TH-expressing cells in the striatal graft between control (n = 5, 2610 ± 942, circles) and PLX (n = 10, 1947 ± 432, squares) mice. b Significant loss in the total number of TH-expressing cells in the ipsilateral versus the contralateral SN in both control (circles) and PLX animals (squares, p > 0.05). Significant loss in the total number of Nissl-stained cells in the ipsilateral versus the contralateral SN in both control and PLX animals (p > 0.05) c There was no significant difference (p > 0.05) in the total number of TH-expressing cells in the striatal graft between animals in the control (n = 6, 1499 ± 159), LPS-injected (n = 13, 1218 ± 142), or IL-4-injected (n = 12, 1097 ± 107) groups. d Significant loss in the total number of TH-expressing cells in the ipsilateral versus the contralateral SN in control, LPS-, and IL-4 injected mice (p > 0.05). Significant loss in the total number of Nissl-stained cells in the ipsilateral versus the contralateral SN in control, LPS-, and IL-4 injected animals (p > 0.05) The error bars represent S.E.M. (TIF 102149 kb)