Additional file 3 of A dysfunctional endolysosomal pathway common to two sub-types of demyelinating Charcot–Marie–Tooth disease

Swollen compartments are accessible to endocytic tracers. Further examples of Fig. 2b. Control or LITAF mutant fibroblasts were incubated with fluid-phase HRP for 4 h before being fixed. A DAB reaction was performed on cells before being processed for conventional electron microscopy.