Additional file 3 of AM1241 inhibits chondrocyte inflammation and ECM degradation through the Nrf2/HO-1 and NF-κB pathways and alleviates osteoarthritis in mice
posted on 2025-01-11, 04:24authored byZhuan Zou, Songmu Pan, Changzheng Sun, Jiyong Wei, Yi Xu, Kaizhen Xiao, Jinmin Zhao, Ronghe Gu
Supplementary Material 3: Molecular dynamics simulation of AM1241 with NEMO/IKKβ. (A) The number of hydrogen bonds formed by AM1241 and NEMO/IKKβ. (B) The radius of gyration (Rg). (C) Protein RMSD frequency distribution during the 50 ns simulation period
Funding
the Natural Science Foundation of Guangxi Province Nanning excellent young scientist program