Additional file 3: Figure S3. of TLR4-NOX2 axis regulates the phagocytosis and killing of Mycobacterium tuberculosis by macrophages

LPS upregulates TLR4 expression in peripheral blood mononuclear cells (PBMCs) from TB patients. PBMCs were isolated from patients with active tuberculosis and healthy volunteers. Age and gender factors were considered to match. In the supplementary experiments, 5 × 105/mL PBMCs from patient or health control were treated with or without 100 ng/mL LPS for 6 h, and TLR4 levels were measured using flow cytometry. The bar graph showed statistical difference of TLR4 levels (*; P < 0.05 compared to health control). (TIFF 265 kb)