12943_2017_593_MOESM3_ESM.tif (89.79 kB)
Additional file 3: Figure S2. of Targeting CD133 improves chemotherapeutic efficacy of recurrent pediatric pilocytic astrocytoma following prolonged chemotherapy
figure
posted on 2017-01-31, 05:00 authored by Guifa Xi, Yuping Li, Gordan Grahovac, Veena Rajaram, Nitin Wadhwani, Tatiana Pundy, Barbara Mania-Farnell, Charles James, Tadanori TomitaInhibition of MDR1 induces cell apoptosis in drug resistant Res186 and Res199 cells. A) Flow cytometry profiles for DOX-R, VIN-R, VCR-R Res186 and Res199 cells, either untreated or treated with 10 μM verapamil for 72 h. B) Number of apoptotic cells based on flow results. (For B, each column represents the mean ± s.d. of a minimum of three independent experiments done in triplicate. ** p < 0.01). (TIF 89 kb)
