Additional file 2 of Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinoma

Additional file 2: Figure S1. A, Ectopic overexpression of survivin compromised xanthohumol-induced cell viability reduction. CAL27 cells were transfected with survivin cDNA and treated with xanthohumol for 24, cell viability was determined by MTS assay. B, CAL27 cells were treated as in “Supplementary Figure 1A”, whole-cell lysate was subjected to cleaved-caspase 3 activity analysis. C, CAL27 cells were treated as in “Supplementary Figure 1A”, whole-cell lysate was subjected to IB analysis. H, CAL27 cells were treated as in “Supplementary Figure 1A”, subcellular fractions were isolated and subjected to IB analysis. ***p < 0.001.