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Additional file 2 of Pilot investigation of circulating angiogenic and inflammatory biomarkers associated with vascular malformations
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posted on 2021-09-04, 03:24 authored by Sarah E. Wetzel-Strong, Shantel Weinsheimer, Jeffrey Nelson, Ludmila Pawlikowska, Dewi Clark, Mark D. Starr, Yingmiao Liu, Helen Kim, Marie E. Faughnan, Andrew B. Nixon, Douglas A. MarchukAdditional file 2: Figure S1. Soluble endoglin levels among HHT patients stratified by genotype. Log-transformed levels of sENG among HHT patients with genotype information were plotted. This analysis included data from 19 HHT1 patients (mutations in ENG), and 11 HHT2 patients (mutations in ACVRL1). Levels were significantly higher in HHT2 patients when adjusting for age and sex in a multivariable linear regression model (PI=1.85, 95% CI: 1.45 to 2.38, p<0.001).
