10020_2019_107_MOESM2_ESM.tif (1.22 MB)
Additional file 2: of Melatonin prevents bone destruction in mice with retinoic acid–induced osteoporosis
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posted on 2019-08-29, 04:54 authored by Xudong Wang, Tongzhou Liang, Yuanxin Zhu, Jincheng Qiu, Xianjian Qiu, Chengjie Lian, Bo Gao, Yan Peng, Anjing Liang, Hang Zhou, Xiaoming Yang, Zhiheng Liao, Yongyong Li, Caixia Xu, Peiqiang Su, Dongsheng HuangFigure S2. Biochemical markers bone metabolism in osteoporosis (OP) mice. Laboratory tests for biochemical markers of bone metabolism. Serum bone metabolism-related indicators RANKL (A), TRACP (B), OPG (C), ALP (D), phosphorus (E), calcium (F), and urinary phosphorus (G), and calcium (H) were determined after the administration of retinoic acid (RA) for 15 d. Control: normal mice, Model: RA-induced OP model mice, Mlt-L: low-dose melatonin-treated OP model mice, Mlt-H: high-dose melatonin-treated OP model mice. Positive control: alendronate-treated OP mice. *, P < 0.05 vs control. #, P < 0.05 vs model; n = 6 per group. (TIF 1247 kb)
