Additional file 1 of IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus
posted on 2021-05-30, 03:23authored byKennedy C. Ukadike, Kathryn Ni, Xiaoxing Wang, Martin S. Taylor, John LaCava, Lauren M. Pachman, Mary Eckert, Anne Stevens, Christian Lood, Tomas Mustelin
Additional file 1: Figure S1. Flow cytometry and gating strategy for two representative pSLE patients. A, first patient: gating on live cells, then single cells, then expression of CD66b or CD19, then p40 in the CD66b+ and CD19+ populations. Note that p40 is predominantly found in the CD66b+ population with higher CD66b expression, presumably activated neutrophils. B, second patient: same gating strategy, showing CD66b+ and CD16+ populations.
Funding
National Institutes of Health Lupus Research Alliance CureJM Foundation