Additional file 1 of IL-23 in arthritic and inflammatory pain development in mice

Additional file 1: Figure S1. Dependence of Csf2, Tnf, Ccl17 and Il23p19 mRNA expression in zymosan-induced arthritis joints. WT, Il23p19-/-, GM-CSF-/-, Tnf-/- and Ccl17E/E mice received an intra-articular (i.a.) injection of saline or zymosan. Joint mRNA expression (day 7) of (A) Csf2, Tnf, Ccl17 and (B) Il23p19 was analyzed. Data are expressed as mean ± SEM; (A-B) WT, Il23p19-/-, GM-CSF-/-, Tnf-/- and Ccl17E/E female mice (saline n=5, zymosan n=8). For statistical analysis, a two-way ANOVA was used. #p<0.05, ##p<0.01, ###p<0.001, saline vs. zymosan. *p<0.05, **p<0.01, ***p<0.001, WT vs. Il23p19-/-, GM-CSF-/- or Tnf-/- mice, respectively.