13046_2021_2166_MOESM1_ESM.tif (1.43 MB)
Additional file 1 of Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
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posted on 2021-11-16, 04:31 authored by Silvia Belluti, Valentina Semeghini, Giovanna Rigillo, Mirko Ronzio, Daniela Benati, Federica Torricelli, Luca Reggiani Bonetti, Gianluca Carnevale, Giulia Grisendi, Alessia Ciarrocchi, Massimo Dominici, Alessandra Recchia, Diletta Dolfini, Carol ImbrianoAdditional file 1: Suppl. Figure S1. Effects of NF-YA inactivation by RNAi in vitro and in vivo. (A) Cell proliferation curve measured by MTT assay of PC3 cells infected with scramble (shCTR) and NF-YA-targeting shRNA (shNF-YA). Data represent mean ± SEM (multiple t-test corrected by the Holm-Sidak method: *p<0.05, **p<0.01, n=4). (B) Images of xenograft tumors dissected from SCID Hairless Outbred (SHO®) mice after 5 weeks from s.c. injection of shCTR and shNF-YA cells (7 mice per group).
