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Additional file 1 of AM1241 inhibits chondrocyte inflammation and ECM degradation through the Nrf2/HO-1 and NF-κB pathways and alleviates osteoarthritis in mice

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posted on 2025-01-11, 04:24 authored by Zhuan Zou, Songmu Pan, Changzheng Sun, Jiyong Wei, Yi Xu, Kaizhen Xiao, Jinmin Zhao, Ronghe Gu
Supplementary Material 1: Figure S1. Molecular docking of AM1241 with Keap1 and NEMO/IKKβ. (A) The detailed connection method between AM1241 and Keap1. (B) The detailed docking method between AM1241 and NEMO/IKKβ. AM1241 is brown, and the blue solid line represents the hydrogen bond distance. (C) Autodock-vina was used for semi-flexible docking and the obtained scores and interaction energy results are shown in the table

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the Natural Science Foundation of Guangxi Province Nanning excellent young scientist program

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