Additional file 1 of α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression
figureposted on 2022-09-01, 04:42 authored by Cheryl A. Hawkes, Christopher J. Heath, Matthew M. Sharp, Dariusz C. Górecki, Roxana O. Carare
Additional File 1: Figure S1. Behavioural outputs of WT and α-DB KO mice on the PR tasks. The breakpoint of α-DB KO mice in the PR4 (a) and PR12 task (b) was significantly higher than WT animals. The majority of WT and KO mice demonstrated persistent responding for the duration of the PR4, PR8 and PR12 schedules (c). In the PR16 schedule, 33% and 42% of WT and KO mice, respectively, continued to engage with the task for the full 60 min. n = 12/group, *p < 0.05, two-tailed Student’s t-test.