Metadata record for the manuscript: Ivermectin converts cold tumors hot and synergies with immune checkpoint blockade for treatment of breast cancer

Summary

This metadata record provides details of the data supporting the claims of the related manuscript: “Ivermectin converts cold tumors hot and synergies with immune checkpoint blockade for treatment of breast cancer ”.

The related study shows that treatment with the FDA-approved anti-parasitic drug ivermectin induces immunogenic cancer cell death (ICD) and robust T cell infiltration into breast tumours.

Type of data: tumour size measurements, flow cytometry, histology

Subject of data: 4T1 cell line, BALB/c (Mus musculus)

Data access

The flow cytometry data (fluorescence-activated cell sorting--FACS) are available upon request from the corresponding author.

Other data generated as part of the related study are tumour size measurements and histology. These are available upon request from the corresponding author.

Corresponding author(s) for this study

Peter P. Lee, M.D., Dept. of Immuno-Oncology, City of Hope and Beckman Research Institute, Beckman Center, room 5117, 1500 East Duarte Road, Duarte, CA 91010. Email: plee@coh.org.

Study approval

All procedures were performed under approval from City of Hope’s Animal Care and Use Committee.