13071_2019_3747_MOESM1_ESM.xlsx (2.9 MB)

MOESM1 of Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery

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posted on 23.10.2019, 08:27 by Martina Maccesi, Pedro Aguiar, Valérian Pasche, Melody Padilla, Brian Suzuki, Sandro Montefusco, Ruben Abagyan, Jennifer Keiser, Marina Mourão, Conor Caffrey
Additional file 1: Table S1. Descriptors and associated severity scores applied by UCSD. Table S2. Concordance between the 3 groups for active and inactive compounds. Table S3. Data transformation. Table S4. Unique hits per group. Table S5. Active compounds shared by all three groups (‘core actives’). Table S6. Transformed activity of the reference compounds. Table S7. Comparisons with data previously generated for the same compounds. Table S8. Transformed activity by disease set. Table S9. Core active compounds compared to activity measured previously by the Swiss TPH against adult S. mansoni.

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H2020 European Research Council

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