Enhancing Genome Editing in hPSCs through Dual Inhibition of DNA Damage Response and Repair Pathways

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posted on 2024-05-12, 07:01 authored by Ju-Chan Park, Yun-Jeong Kim, Chan Young Kang, Sangsu Bae, Hyuk-Jin Cha, Gue-Ho Hwang

Improving cytosine base editor (CBE) and prime editor (PE) in human pluripotent stem cells (hPSCs) via dual inhibition of DNA damage response and DNA repair pathways