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13293_2020_312_MOESM9_ESM.xlsx (13.07 kB)

Additional file 9 of Reference genome and transcriptome informed by the sex chromosome complement of the sample increase ability to detect sex differences in gene expression from RNA-Seq data

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posted on 2020-07-22, 06:11 authored by Kimberly C. Olney, Sarah M. Brotman, Jocelyn P. Andrews, Valeria A. Valverde-Vesling, Melissa A. Wilson
Additional file 9: Paired t-test for mapped reads in default compared to sex chromosome complement reference genome. Mean difference in expression for average total reads mapped for each tissue and each sex when aligned to a sex chromosome informed versus a default reference genome. Paired t-test to test for significant difference in total reads mapped for the whole transcriptome (WT), chromosome 8, and chromosome X. Nonparametric Wilcox single rank sum test was used to test for significant difference in total reads mapped on the Y chromosome for male samples in each tissue separately.


National Institute of General Medical Sciences (US) Biodesign Institute, Arizona State University (US) School of Life Sciences, Arizona State University (US)


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    Biology of Sex Differences