13075_2023_3073_MOESM5_ESM.zip (9.6 MB)
Additional file 5 of Lymphocyte activation gene 3 is increased and affects cytokine production in rheumatoid arthritis
dataset
posted on 2023-06-08, 03:21 authored by Janni Maria Pedersen, Aida Solhøj Hansen, Cæcilie Skejø, Kristian Juul-Madsen, Peter Junker, Kim Hørslev-Petersen, Merete Lund Hetland, Kristian Stengaard-Pedersen, Mikkel Østergaard, Bjarne Kuno Møller, Lene Dreyer, Ellen-Margrethe Hauge, Malene Hvid, Stinne Greisen, Bent DeleuranAdditional file 5: Fig. S5. Effects of rhLAG-3 and anti-LAG3-mAb on cytokine production in the presence of a Gal-3 inhibitor. Production of cytokines in recombinant human LAG-3 treated (A) and anti-LAG3-mAb (B) treated PBMC and SFMC cultures from RA patients (n = 11) with or without addition of Galectin-3 inhibitor. Level of significance is indicated by * < 0.05. Differences were analyzed using the Mann-Whitney test to compare two groups.
