posted on 2024-08-15, 03:15authored byHao Zhang, Ryan M. Mulqueen, Natalie Iannuzo, Dominique O. Farrera, Francesca Polverino, James J. Galligan, Julie G. Ledford, Andrew C. Adey, Darren A. Cusanovich
Additional file 4: Table S3. KEGG pathways enriched in differential peaks between CC16-/- and WT samples for each cell type. This table is provided as a separate file. Column 1: Cell type in which the test was performed. Column 2: KEGG pathway ID. Column 3: Description of KEGG pathway. Column 4: Fraction of non-gap base pairs in the genome that lie in the regulatory domain of a gene with the annotation. Column 5: Actual number of differential peaks with the annotation. Column 6: Fold enrichment of number of differential peaks with the annotation. Column 7: Uncorrected p-value from the binomial test over genomic regions. Column 8: FDR-adjusted p-value for the binomial test. Column 9: Mean absolute distance of input regions to TSS of genes in a gene set. Column 10: Actual number of genes linking to a differential peak with the annotation. Column 11: Number of genes in the genome with the annotation. Column 12: Fold enrichment of number of genes linking to a differential peak with the annotation. Column 13: Uncorrected p-value from the hypergeometric test over genes. Column 14: FDR-adjusted p-value for the hypergeometric test.
Funding
National Institute of General Medical Sciences National Institute of Mental Health National Institute of Environmental Health Sciences National Heart, Lung, and Blood Institute