Additional file 3 of A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population

Additional file 3: Supplement Table 2. RNAseq cancer gene hotspot mutations detected in 151 KTB samples. Sheet 1 identifies the > 5100 unthresholded cancer mutation hotspot calls from the KTB RNAseq analysis occurring in the combined set of MSK-IMPACT curated cancer hotspot clinical targets [10] and the experimentally determined RNAseq identified set of expressed cancer gene hotspot mutations within > 6700 normal GTEx human tissue samples as recently described [11]. Sheet 2 (“normal_breast_rna.getz_list.092”) lists only those > 1760 cancer gene hotspot mutations from sheet 1 meeting the threshold mutation likelihood score > 5, while sheets 3 and 4 list the thresholded hotspot mutations according to F and P sample batches with each sample phenotyped as either Active or Inactive. Sheet 5 is a sample key mapping all KTB identification numbers, barcodes, and UUID numbers pertaining to the RNAseq results and cancer gene hotspot mutation calls. Of note, Fig. 2 panels (“Breast sample scatterplots and TumorMaps of RNA expressed cancer hotspot mutations”) include plots derived from the curated and thresholded hotspot mutations as listed in sheet 2.