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Additional file 2 of Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations
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posted on 2022-01-08, 04:24 authored by Charles E. Breeze, Eric Haugen, Alex Reynolds, Andrew Teschendorff, Jenny van Dongen, Qing Lan, Nathaniel Rothman, Guillaume Bourque, Ian Dunham, Stephan Beck, John Stamatoyannopoulos, Nora Franceschini, Sonja I. BerndtAdditional file 2: Table S1. Consolidated Epigenomics Roadmap DNase I hotspot FORGE2 GWAS catalogue analysis results (q-values).
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underlying regulatory mechanismssingle nucleotide polymorphismsfriendly web toolforge web toolactive regulatory elementsspecific repressed regionsspecific regulatory elementswide association study60 associations specific400 associations specific30 associations specificrepressive chromatin statesdifferent chromatin stateshttps :// forge2cell types relevantassociated cell typemediated disease aetiologychromatin statescell typescell typedisease aetiologyspecific signalsspecific regulationspecific enrichmentstissue associationsdisease risktissue associationupdated versionpreferentially coloci discoveredhistone marksgain insightforge2 usesexpanded atlasepigenomic marksdeveloped forge2also detected
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