13059_2021_2585_MOESM2_ESM.xlsx (893.19 kB)
Additional file 2 of Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression
dataset
posted on 2022-01-15, 05:56 authored by Thomas H. Jonkman, Koen F. Dekkers, Roderick C. Slieker, Crystal D. Grant, M. Arfan Ikram, Marleen M. J. van Greevenbroek, Lude Franke, Jan H. Veldink, Dorret I. Boomsma, P. Eline Slagboom, B. I. O. S. Consortium, Bastiaan T. HeijmansAdditional file 2: Table S1. All associations between clock CpG methylation and expression of genes in cis and in trans as identified by the regression analysis.
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Nederlandse Organisatie voor Wetenschappelijk Onderzoek Foundation for the National Institutes of Health
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related health outcomes40 years youngersimilar histone modificationsincluding hannum ’finding may contributefour clocks resultnk cell activationgene sets involvedfunctional genomics analysisfour epigenetic clocksindividual chronological ageepigenetic clocksspecific setssimilar predictionsnk cellsmay drivehorvath ’gene expressionchronological agewide applicationtissue predictorprobable contributorpredicted agepotential biomarkerpopular applicationlimited insighthighly overlappingexplore whetherestablished featuredisease phenotypesdetect changesderived measurescpg dinucleotideschromatin statescell processesblood predictorbiological age3132 individuals
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