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Additional file 2 of Characterisation of an inflammation-related epigenetic score and its association with cognitive ability

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posted on 2020-07-28, 05:23 authored by Anna J. Stevenson, Daniel L. McCartney, Robert F. Hillary, Archie Campbell, Stewart W. Morris, Mairead L. Bermingham, Rosie M. Walker, Kathryn L. Evans, Thibaud S. Boutin, Caroline Hayward, Allan F. McRae, Barry W. McColl, Tara L. Spires-Jones, Andrew M. McIntosh, Ian J. Deary, Riccardo E. Marioni
Additional file 2: Table S1. CpG sites and relative weights (from Lighthart et al.) used to generate the DNAm CRP score. Table S2. SNPs and relative weights (from Dehghan et al.) used to generate the genetic score for CRP. Table S3. Summary of latent class analyses for log(CRP) and the DNAm CRP score in the Lothian Birth Cohort 1936. Table S4. Associations with determinants of CRP and the genetic CRP score. Table S5. Association between individual CpG sites and general cognitive ability (gf) in the Lothian Birth Cohort 1936 and Generation Scotland. Table S6. Longitudinal associations between the baseline DNAm CRP score and serum CRP and general cognitive ability (gf) over the four waves of follow-up in the Lothian Birth Cohort 1936.

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Wellcome Trust Medical Research Council Alzheimer’s Research UK

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