12936_2021_3979_MOESM2_ESM.xlsx (12.8 MB)
Additional file 2 of Analysis of pir gene expression across the Plasmodium life cycle
dataset
posted on 2021-11-26, 05:15 authored by Timothy S. Little, Deirdre A. Cunningham, Audrey Vandomme, Carlos Talavera Lopez, Sarah Amis, Christopher Alder, John W. G. Addy, Sarah McLaughlin, Caroline Hosking, George Christophides, Adam J. Reid, Jean LanghorneAdditional file 2. P. berghei pirgene information, TPM values for individual samples and combined across life cycle stages, and summed across sub-families, chromosomes and loci.
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francis crick institute imperial college london wellcome trust The Francis Crick Institute
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red blood cellsincluding antigenic variationdistinct expression patternspir gene transcriptspir gene expressionmale gametocytes producelargest multigene familydetermine function experimentallystudied plasmodium speciesdifferent pir genesplasmodium speciespir genesresults expressionproduce relativelyfemale gametocytesdifferent timesplasmodium chabaudipir proteinssuggest rolesrepetitive naturepotential tractabilitynotably comparedmarked exceptionliver merozoiteslife cyclelarge numberinvestigation dueimportant roleimmune evasionhighly transcribedhigh resolutionfuture experimentsfunctional investigationfunctional distinctionsdirect evidencechronic infection
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