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Additional file 2 of An epigenome-wide association study of insulin resistance in African Americans

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posted on 2022-07-15, 07:55 authored by Felix P. Chilunga, Karlijn A. C. Meeks, Peter Henneman, Charles Agyemang, Ayo P. Doumatey, Charles N. Rotimi, Adebowale A. Adeyemo
Additional file2. Table S1. List of CpG sites within the HOXA5 DMR; Table S2. Previously reported EWAS for insulin resistance; Table S3. DMPs reported in previous insulin resistance EWAS; Table S4. Association between candidate CpG sites reported in previous studies and HOMA-IR in African American men.Table S5. Summary statistics from the main HOMA-IR analysis in African American men for candidate CpG sites; Table S6. Candidate probes that successfully replicated in African American men; Table S7a. Chromatin states of top 100 DMPs associated with insulin resistance in African American men from clusterProfiler; Table S7b. Chromatin states of top 100 DMPs associated with insulin resistance in African American men from the EWAS Toolkit; Table S8. Gene function and associated phenotypes in GWAS catalog and GeneCards; Table S9A. Traits associated with the three identified DMPs (annotated genes) in the EWAS catalog; Table S9B. Traits associated with genes in the 500kb vicinity of HOXA5, OSR1, and ST18 in the EWAS catalog; Table S10. R packages used in the analyses.

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European Foundation for the Study of Diabetes National Human Genome Research Institute NIH Office of the Director National Institutes of Health (NIH)

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