Additional file 1 of Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination

dataset

posted on 2023-04-13, 16:14 authored by Hyunbin D. Huh, Yujin Sub, Jongwook Oh, Ye Eun Kim, Ju Young Lee, Hwa-Ryeon Kim, Soyeon Lee, Hannah Lee, Sehyung Pak, Sebastian E. Amos, Danielle Vahala, Jae Hyung Park, Ji Eun Shin, So Yeon Park, Han Sang Kim, Young Hoon Roh, Han-Woong Lee, Kun-Liang Guan, Yu Suk Choi, Joon Jeong, Junjeong Choi, Jae-Seok Roe, Heon Yung Gee, Hyun Woo Park

Additional file 1: Movie S1. Induction and reversibility of AST in HEK293A-ASTTetR cells. Video 1. Video of HEK293A-ASTTetR cell proliferation in normal culture condition. Video 2. Video of HEK293A-ASTTetR cell proliferation after doxycycline treatment. Video 3. Video of HEK293A-ASTTetR cell proliferation after doxycycline removal.

History

Usage metrics

Categories

Keywords

upregulate globin genes suppress global integrin reprograms anchorage dependency reprogramming anchorage dependency reprogram anchorage dependency prevent oxidative stress cell rna sequencing biological phenomenon referred analyzed blood cell acquire anoikis resistance solid tumor cells circulating tumor cells primary tumor growth de novo metastasis confer metastatic traits selected key adherent reprograms adherent cells adherent cells 1 defined hematopoietic factors metastatic dissemination remains adherent cells suspension cells primary tumors metastatic tumors metastatic spread block metastasis vivo assays tissue staining tead inhibition suspension transition specific transcripts specialized mechanism shrna knockdown reversible manner related death prolong survival pharmacological inhibition pharmacological blockade paired samples mouse models lineage differentiation gene editing function experiments foremost cause findings expand directly arise critical roles critical area

Licence

Exports

RefWorks

BibTeX

Ref. manager

Endnote

DataCite

NLM

DC