13148_2020_906_MOESM1_ESM.zip (7.11 MB)
Additional file 1 of Circulating unmethylated CHTOP and INS DNA fragments provide evidence of possible islet cell death in youth with obesity and diabetes
dataset
posted on 2020-08-01, 07:12 authored by Farooq Syed, Sarah A. Tersey, Jean-Valery Turatsinze, Jamie L. Felton, Nicole Jiyun Kang, Jennifer B. Nelson, Emily K. Sims, Mathieu Defrance, Martin Bizet, Francois Fuks, Miriam Cnop, Marco Bugliani, Piero Marchetti, Anette-Gabriele Ziegler, Ezio Bonifacio, Bobbie-Jo Webb-Robertson, Appakalai N. Balamurugan, Carmella Evans-Molina, Decio L. Eizirik, Kieren J. Mather, Silva Arslanian, Raghavendra G. MirmiraAdditional file 1. Supplemental Table S1: Human Islet Donor Characteristics. Supplemental Table S2: Human tissues/cell lines used as controls for Illumina 450-Array. Supplemental Table S3: Primers for sequencing. Supplemental Table S4: Table of all differentially methylated CpGs. Supplemental Figure S1: Experimental Workflow. Supplemental Figure S2: Immunofluorescence staining of flow-sorted human β cells.