13148_2016_193_MOESM1_ESM.xls (461.5 kB)

Additional file 1: Table S1. of Genome-wide analysis of DNA methylation and gene expression defines molecular characteristics of Crohn’s disease-associated fibrosis

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posted on 12.03.2016, 05:00 by Tammy Sadler, Jeffrey Bhasin, Yaomin Xu, Jill Barnholz-Sloan, Yanwen Chen, Angela Ting, Eleni Stylianou
Differentially methylated regions (DMRs) between normal and fibrotic HIF. Each row represents one DMR. For each DMR, a unique ID, coordinates in the form of chr, start, end (hg19), and the DMR width are provided. Each DMR is categorized by a pattern code: “01” represents hypermethylation in fibrotic samples, and “10” represents hypomethylation in fibrotic samples. The “ratio” column represents the magnitude of the difference in sequencing signal as a log2 fold change, “p.value” is the unadjusted p value, and “q.value” is the Benjamini-Hochberg adjusted p value. “Genomic_context” specifies if the DMR falls within a portion of an annotated gene model. Multiple overlaps are resolved using the priority: promoter > exon > intron > 3′ end > intergenic. Overlap with CpG shores, islands, and shelves is provided, along with the distance to the nearest gene and the names of the nearest genes. (XLS 461 kb)

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