Additional file 16 of PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

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posted on 2025-01-11, 04:24 authored by Vasudha Mishra, Alka Singh, Michael Korzinkin, Xiangying Cheng, Claudia Wing, Viktoria Sarkisova, Ashwin L. Koppayi, Alexandra Pogorelskaya, Oksana Glushchenko, Manu Sundaresan, Venkat Thodima, Jack Carter, Koichi Ito, Peggy Scherle, Anna Trzcinska, Ivan Ozerov, Everett E. Vokes, Grayson Cole, Frank W. Pun, Le Shen, Yuxuan Miao, Alexander T. Pearson, Mark W. Lingen, Bruce Ruggeri, Ari J. Rosenberg, Alex Zhavoronkov, Nishant Agrawal, Evgeny Izumchenko

Supplementary Table 9: Baseline in vivo responsiveness to various therapeutic agents in ACC PDX models (data obtained from the ACC Research Foundation)

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National Institutes of Health

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Keywords

Adenoid cystic carcinoma (ACC)Protein arginine methyl transferase 5 (PRMT5)Organoid models Patient derived xenografts (PDXs)PandaOmics Whole exome sequencing RNA-Seq

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